Title : Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome.

Pub. Date : 2011 Jun 15

PMID : 21464611






1 Functional Relationships(s)
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1 The release of IL-1beta required the expression of ASC, caspase-1, and NLRP3, demonstrating that doxorubicin and daunorubicin-induced inflammation is mediated by the NLRP3 inflammasome. Daunorubicin steroid sulfatase Mus musculus