Title : Sodium fluoride suppress proliferation and induce apoptosis through decreased insulin-like growth factor-I expression and oxidative stress in primary cultured mouse osteoblasts.

Pub. Date : 2011 Nov

PMID : 21461751






3 Functional Relationships(s)
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1 Sodium fluoride suppress proliferation and induce apoptosis through decreased insulin-like growth factor-I expression and oxidative stress in primary cultured mouse osteoblasts. Sodium Fluoride insulin-like growth factor 1 Mus musculus
2 On the other hand, we found that NaF increased oxidative stress and decreased protein expression of IGF-I. Sodium Fluoride insulin-like growth factor 1 Mus musculus
3 Our study herein suggested that NaF caused proliferation suppression, and apoptosis may contribute to decrease IGF-I expression and increased oxidative stress damage by NaF in the primary mouse osteoblasts. Sodium Fluoride insulin-like growth factor 1 Mus musculus