Pub. Date : 2011 May 20
PMID : 21454520
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this study, we found that wild type p53 is induced by arsenic trioxide in tumor cells, consistent with published studies. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |
2 | We also found that arsenic trioxide decreases the stability of mutant p53 protein through a proteasomal pathway, and blockage of mutant p53 nuclear export can alleviate the arsenic-induced mutant p53 degradation. | Arsenic Trioxide | tumor protein p53 | Homo sapiens |