Title : Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling.

Pub. Date : 2011 Jul

PMID : 21439372






1 Functional Relationships(s)
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1 Oral administration of resveratrol to diabetic rats showed a significant normalization on the levels of creatinine clearance, plasma adiponectin, C-peptide and renal superoxide anion, hydroxyl radical, nitric oxide, TNF-alpha, IL-1beta, IL-6 and NF-kappaB p65 subunit and activities of renal aspartate transaminase, alanine transaminase and alkaline phosphatase in comparison with diabetic rats. Resveratrol adiponectin, C1Q and collagen domain containing Rattus norvegicus