Title : Cytochrome P450-dependent metabolism in HepaRG cells cultured in a dynamic three-dimensional bioreactor.

Pub. Date : 2011 Jul

PMID : 21436404






1 Functional Relationships(s)
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1 Ketoconazole treatment decreased the CYP3A4 activity by 69%, and rifampicin induced the CYP3A4- and CYP2B6-dependent activity 6-fold, which predicts well the magnitude of changes observed in vivo. Rifampin cytochrome P450 family 2 subfamily B member 6 Homo sapiens