Title : Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance.

Pub. Date : 2012 Jan

PMID : 21414769






2 Functional Relationships(s)
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Protein Name
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1 Kuguacin J also inhibited the incorporation of [125I]-iodoarylazidoprazosin into P-gp in a concentration-dependent manner, indicating that kuguacin J directly interacts with the drug-substrate-binding site on P-gp. azidoprazosin phosphoglycolate phosphatase Homo sapiens
2 Kuguacin J also inhibited the incorporation of [125I]-iodoarylazidoprazosin into P-gp in a concentration-dependent manner, indicating that kuguacin J directly interacts with the drug-substrate-binding site on P-gp. azidoprazosin phosphoglycolate phosphatase Homo sapiens