Title : COX-2-dependent and COX-2-independent mode of action of celecoxib in human liver cancer cells.

Pub. Date : 2011 Jun

PMID : 21410330






2 Functional Relationships(s)
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1 To better understand COX-2-independent molecular mechanisms underlying the antitumor activity of celecoxib, we investigated the expression profile of the celecoxib-treated COX-2-positive (Huh7) and COX-2-negative (HepG2) liver cancer cell lines, using microarray analysis. Celecoxib MIR7-3 host gene Homo sapiens
2 Celecoxib treatment resulted in significantly altered expression levels of 240 and 403 transcripts in Huh7 and HepG2 cells, respectively. Celecoxib MIR7-3 host gene Homo sapiens