Title : [Clinical pharmacokinetics of an imipenem-cilastatin combination].

Pub. Date : 1990 Apr 4

PMID : 2139939






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1 However, when the dehydropeptidase I inhibitor cilastatin is given concomitantly with imipenem the urinary excretion and clearance of imipenem reach similar values in all subjects; in addition, the antibiotic is better tolerated by the kidney. Imipenem dipeptidase 1 Homo sapiens
2 However, when the dehydropeptidase I inhibitor cilastatin is given concomitantly with imipenem the urinary excretion and clearance of imipenem reach similar values in all subjects; in addition, the antibiotic is better tolerated by the kidney. Imipenem dipeptidase 1 Homo sapiens