Pub. Date : 2012 Jan 15
PMID : 21387297
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we report that JG3 inhibits NF-kappaB activation by specifically antagonizing the doxorubicin-triggered Ataxia-telangiectasia-mutated kinase (ATM) and the sequential MEK/ERK/p90Rsk/IKK signaling pathway but does not interfere with TNF-alpha-mediated NF-kappaB activation. | Doxorubicin | tumor necrosis factor | Homo sapiens |