Title : The antiandrogenic effect of finasteride against a mutant androgen receptor.

Pub. Date : 2011 May 15

PMID : 21386657






2 Functional Relationships(s)
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Protein Name
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1 In Prx1-rich LNCaP cells, the combination of Prx1 knockdown and finasteride was found to produce a greater inhibitory effect on AR activity and cell growth than either treatment alone. Finasteride peroxiredoxin 1 Homo sapiens
2 The observation suggests that cells with a low expression of Prx1 are likely to be more responsive to the antiandrogenic effect of finasteride. Finasteride peroxiredoxin 1 Homo sapiens