Title : Determinants of ligand binding affinity and cooperativity at the GLUT1 endofacial site.

Pub. Date : 2011 Apr 19

PMID : 21384913






5 Functional Relationships(s)
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Protein Name
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1 Cytochalasin B (CB) and forskolin (FSK) inhibit GLUT1-mediated sugar transport in red cells by binding at or close to the GLUT1 endofacial sugar binding site. Sugars solute carrier family 2 member 1 Homo sapiens
2 Cytochalasin B (CB) and forskolin (FSK) inhibit GLUT1-mediated sugar transport in red cells by binding at or close to the GLUT1 endofacial sugar binding site. Sugars solute carrier family 2 member 1 Homo sapiens
3 Cytochalasin B (CB) and forskolin (FSK) inhibit GLUT1-mediated sugar transport in red cells by binding at or close to the GLUT1 endofacial sugar binding site. Sugars solute carrier family 2 member 1 Homo sapiens
4 Cytochalasin B (CB) and forskolin (FSK) inhibit GLUT1-mediated sugar transport in red cells by binding at or close to the GLUT1 endofacial sugar binding site. Sugars solute carrier family 2 member 1 Homo sapiens
5 We discuss this result within the context of models for GLUT1-mediated sugar transport and GLUT1 quaternary structure, and we evaluate the major determinants of ligand binding affinity and cooperativity. Sugars solute carrier family 2 member 1 Homo sapiens