Title : TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.

Pub. Date : 2011 Mar 7

PMID : 21383078






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 Cyclic adenosine monophosphate response element modulator (CREM) and TRF2, key transcription factors for spermiogenesis, are expressed in Tdrd5-deficient round spermatids, but their targets, including Prm1/Prm2/Tnp1, are severely down-regulated, which indicates the importance of IMC/CB-mediated regulation for postmeiotic gene expression. Cyclic AMP protamine 1 Mus musculus