Title : A phase I study evaluating the effect of CDHP as a component of S-1 on the pharmacokinetics of 5-fluorouracil.

Pub. Date : 2011 Feb

PMID : 21378348






1 Functional Relationships(s)
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1 Following single- and multiple-dose administration of S-1, plasma concentrations of uracil returned to baseline levels within approximately 48 h of dosing, indicating reversibility of DPD inhibition by CDHP. Uracil proteasome 26S subunit, non-ATPase 1 Homo sapiens