Title : Ginsenoside Rh2 inhibits glioma cell proliferation by targeting microRNA-128.

Pub. Date : 2011 Mar

PMID : 21372826






1 Functional Relationships(s)
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1 In U251 cells, transfection of a miR-128 inhibitor (50 nmol/L) prevented the overexpression of miR-128 by Rh2, and significantly blunted Rh2-induced cytotoxicity, apoptosis, caspase 3 activation, transcriptional activation of E2F3a, a miR-128 target gene, as well as E2F3a protein expression. mir-128 caspase 3 Homo sapiens