Title : Differential regulation of C-terminal splice variants of the glutamate transporter GLT-1 by tumor necrosis factor-alpha in primary cultures of astrocytes.

Pub. Date : 2011 Jun

PMID : 21371514






1 Functional Relationships(s)
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1 While GLT-1a and GLT-1b mRNAs were both increased in response to treatment with N(6),2"-O-dibutyryladenosine 3",5"-cyclic monophosphate (dBcAMP), the culture supplement G5 or tumor necrosis factor-alpha (TNF-alpha), the regulation of GLT-1b appeared quicker and was more pronounced. Bucladesine tumor necrosis factor Homo sapiens