Title : Farnesoid X receptor, overexpressed in pancreatic cancer with lymph node metastasis promotes cell migration and invasion.

Pub. Date : 2011 Mar 15

PMID : 21364590






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The function of FXR was studied by small interfering RNA and treatment with FXR antagonist guggulsterone and FXR agonist GW4064. pregna-4,17-diene-3,16-dione nuclear receptor subfamily 1 group H member 4 Homo sapiens
2 Small interfering RNA-mediated downregulation of FXR and guggulsterone-mediated FXR inhibition resulted in a marked reduction in cell migration and invasion. pregna-4,17-diene-3,16-dione nuclear receptor subfamily 1 group H member 4 Homo sapiens