Title : [Dual effects of extract of Schisandra chinensis Baill on rat hepatic CYP3A].

Pub. Date : 2010 Sep

PMID : 21351579






2 Functional Relationships(s)
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1 Aqueous extract of WWZ could induce the enzyme activity of CYP3A after 6-day gavage. SLC-0111 cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus
2 Aqueous extract of WWZ and kadsurin showed a dose-dependent inhibition of CYP3A (IC50 of 487.8 microg mL(-1) and 6.2 micromol L(-1), separately). SLC-0111 cytochrome P450, family 3, subfamily a, polypeptide 62 Rattus norvegicus