Pub. Date : 2011 Apr 15
PMID : 21349833
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We identify the primary cause of inhibition as a failure to activate the nucleotide base as an efficient leaving group and demonstrate that the higher binding affinity of AAG for epsilonC versus epsilonA is achieved through formation of an additional hydrogen bond between Asn-169 in the active site pocket and the O(2) of epsilonC. | Asparagine | N-methylpurine DNA glycosylase | Homo sapiens |