Title : Pre-synaptic glycine GlyT1 transporter--NMDA receptor interaction: relevance to NMDA autoreceptor activation in the presence of Mg2+ ions.

Pub. Date : 2011 May

PMID : 21348870






1 Functional Relationships(s)
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1 The NMDA/glycine-induced release in 1.2 mM Mg(2+) strictly depended on glycine uptake through the glycine transporter type 1 (GlyT1), because the GlyT1 blocker N-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride, but not the GlyT2 blocker Org 25534, prevented it. n-[3-(4"-fluorophenyl)-3-(4"-phenylphenoxy)propyl])sarcosine hydrochloride solute carrier family 6 member 5 Rattus norvegicus