Title : Phosphate and Klotho.

Pub. Date : 2011 Apr

PMID : 21346722






1 Functional Relationships(s)
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1 Klotho-/- mice display premature aging and chronic kidney disease-associated mineral and bone disorder (CKD-MBD)-like phenotypes mediated by hyperphosphatemia and remediated by phosphate-lowering interventions (diets low in phosphate or vitamin D; knockouts of 1alpha-hydroxylase, vitamin D receptor, or NaPi cotransporter). Vitamin D klotho Mus musculus