Pub. Date : 2011 Feb
PMID : 21336733
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study examined the effect of nicotine on the expression of mutant p53 (mt-p53) in bladder cancer rats. | Nicotine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 2 | This study examined the effect of nicotine on the expression of mutant p53 (mt-p53) in bladder cancer rats. | Nicotine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 3 | The positive rate of mt-p53 expression in the 3 nicotine groups (25, 15, 5 mg/kg) was 75.00%, 58.33% and 41.67% by the 14th week, respectively, significantly higher than that in the MNU group (33.33%) (all P<0.05). | Nicotine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 4 | It is concluded that nicotine may play an important role in the development of bladder cancer partially by increasing the expression of mt-p53. | Nicotine | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |