Title : IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.

Pub. Date : 2011 Mar

PMID : 21317537






1 Functional Relationships(s)
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1 Here, we have shown that pancreatic ductal secretion in mice is suppressed by silencing of the NBCe1-B/CFTR activator inositol-1,4,5-trisphosphate (IP(3)) receptor-binding protein released with IP(3) (IRBIT) and by inhibition of protein phosphatase 1 (PP1). ip cystic fibrosis transmembrane conductance regulator Mus musculus