Title : Regulation of AMP-activated protein kinase by LKB1 and CaMKK in adipocytes.

Pub. Date : 2011 May

PMID : 21312243






2 Functional Relationships(s)
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1 The inhibition of CaMKK isoforms, particularly CaMKKbeta, by the inhibitor STO-609 or by siRNAs, blocked Ca(2+) -, but not phenformin-, AICAR-, or forskolin-induced activation of AMPK, indicating that CaMKK activated AMPK in response to Ca(2+) . Phenformin calcium/calmodulin-dependent protein kinase kinase 1, alpha Mus musculus
2 The inhibition of CaMKK isoforms, particularly CaMKKbeta, by the inhibitor STO-609 or by siRNAs, blocked Ca(2+) -, but not phenformin-, AICAR-, or forskolin-induced activation of AMPK, indicating that CaMKK activated AMPK in response to Ca(2+) . Phenformin calcium/calmodulin-dependent protein kinase kinase 1, alpha Mus musculus