Title : Suppression of choroidal neovascularization and quantitative and qualitative inhibition of VEGF and CCL2 by heparin.

Pub. Date : 2011 May 16

PMID : 21296829






3 Functional Relationships(s)
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Protein Name
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1 Suppression of choroidal neovascularization and quantitative and qualitative inhibition of VEGF and CCL2 by heparin. Heparin C-C motif chemokine ligand 2 Homo sapiens
2 Relative decreases in VEGF and CCL2 levels were observed in media of ARPE19 cells at higher heparin concentrations. Heparin C-C motif chemokine ligand 2 Homo sapiens
3 Reduced VEGF and CCL2 secretion by RPE cells and suppression of VEGF-VEGFR2 and CCL2-CCR2 interactions at the laser site mediated by heparin may contribute to the pharmacologic effect. Heparin C-C motif chemokine ligand 2 Homo sapiens