Title : Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b.

Pub. Date : 2011 May

PMID : 21292642






1 Functional Relationships(s)
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1 We found that prolonged exposure of immortalized p53-knocked down human bronchial epithelial cells (p53(low)HBECs) to low levels of arsenite (NaAsO2, 2.5 muM) caused malignant transformation that was accompanied by epithelial to mesenchymal transition (EMT) and reduction in the levels of miR-200 family members. sodium arsenite tumor protein p53 Homo sapiens