Pub. Date : 2011 Jun
PMID : 21289292
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxygen consumption and cellular ATP levels were reduced in BAX-deficient cells, while glycolysis was increased. | Adenosine Triphosphate | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 2 | These results suggested that cells lacking BAX have a deficiency in the ability to generate ATP through cellular respiration. | Adenosine Triphosphate | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 3 | Inhibition of BAX with small interfering RNAs reduced intracellular ATP content in BAX-containing cells. | Adenosine Triphosphate | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 4 | Inhibition of BAX with small interfering RNAs reduced intracellular ATP content in BAX-containing cells. | Adenosine Triphosphate | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 5 | Expression of either full-length or COOH-terminal-truncated BAX in BAX-deficient cells rescued ATP synthesis and oxygen consumption and reduced glycolytic activity, suggesting that this metabolic function of BAX was not dependent upon its COOH-terminal helix. | Adenosine Triphosphate | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 6 | Expression of BCL-2 in BAX-containing cells resulted in a subsequent loss of ATP measured, implying that, even under nonapoptotic conditions, an antagonistic interaction exists between the two proteins. | Adenosine Triphosphate | BCL2 associated X, apoptosis regulator | Homo sapiens |