Pub. Date : 2011 May
PMID : 21278233
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Although diverse compounds reduce the hERG current (I(hERG)) by blocking the channel, probucol, a cholesterol-lowering drug that causes LQTS, reduces I(hERG) by decreasing plasma-membrane hERG protein expression. | Probucol | ETS transcription factor ERG | Homo sapiens |
| 2 | Although diverse compounds reduce the hERG current (I(hERG)) by blocking the channel, probucol, a cholesterol-lowering drug that causes LQTS, reduces I(hERG) by decreasing plasma-membrane hERG protein expression. | Probucol | ETS transcription factor ERG | Homo sapiens |
| 3 | Although diverse compounds reduce the hERG current (I(hERG)) by blocking the channel, probucol, a cholesterol-lowering drug that causes LQTS, reduces I(hERG) by decreasing plasma-membrane hERG protein expression. | Probucol | ETS transcription factor ERG | Homo sapiens |
| 4 | The effects of probucol on Cav1 and hERG result from probucol"s cholesterol-disrupting action, because low-density lipoprotein (LDL), a potent cholesterol carrier, effectively prevented probucol-induced reduction of I(hERG) in hERG-expressing HEK cells and of I(Kr) in neonatal rat cardiomyocytes. | Probucol | ETS transcription factor ERG | Homo sapiens |
| 5 | The effects of probucol on Cav1 and hERG result from probucol"s cholesterol-disrupting action, because low-density lipoprotein (LDL), a potent cholesterol carrier, effectively prevented probucol-induced reduction of I(hERG) in hERG-expressing HEK cells and of I(Kr) in neonatal rat cardiomyocytes. | Probucol | ETS transcription factor ERG | Homo sapiens |
| 6 | The effects of probucol on Cav1 and hERG result from probucol"s cholesterol-disrupting action, because low-density lipoprotein (LDL), a potent cholesterol carrier, effectively prevented probucol-induced reduction of I(hERG) in hERG-expressing HEK cells and of I(Kr) in neonatal rat cardiomyocytes. | Probucol | ETS transcription factor ERG | Homo sapiens |