Title : Doxorubicin loaded iron oxide nanoparticles overcome multidrug resistance in cancer in vitro.

Pub. Date : 2011 May 30

PMID : 21277920






1 Functional Relationships(s)
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1 Doxorubicin (DOX), an anthracycline antibiotic commonly used in cancer chemotherapy and substrate for ABC-mediated drug efflux, was covalently bound to polyethylenimine via a pH sensitive hydrazone linkage and conjugated to an iron oxide nanoparticle coated with amine terminated polyethylene glycol. Polyethylene Glycols ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens