Title : Activation and up-regulation of translation initiation factor 4B contribute to arsenic-induced transformation.

Pub. Date : 2011 Jul

PMID : 21268130






3 Functional Relationships(s)
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1 The phosphorylation of AKT and its downstream targets, 70-kDa ribosomal protein S6 kinase (p70S6K) and translation initiation factor 4B (eIF4B), are increased in the arsenite treated cells, indicating that long-term arsenite treatment activates AKT-p70S6K signaling pathway. arsenite AKT serine/threonine kinase 1 Homo sapiens
2 The phosphorylation of AKT and its downstream targets, 70-kDa ribosomal protein S6 kinase (p70S6K) and translation initiation factor 4B (eIF4B), are increased in the arsenite treated cells, indicating that long-term arsenite treatment activates AKT-p70S6K signaling pathway. arsenite AKT serine/threonine kinase 1 Homo sapiens
3 The phosphorylation of AKT and its downstream targets, 70-kDa ribosomal protein S6 kinase (p70S6K) and translation initiation factor 4B (eIF4B), are increased in the arsenite treated cells, indicating that long-term arsenite treatment activates AKT-p70S6K signaling pathway. arsenite AKT serine/threonine kinase 1 Homo sapiens