Title : Inhibition of cytochrome P450 2A participating in coumarin 7-hydroxylation in pig liver microsomes.

Pub. Date : 2011 Oct

PMID : 21244437






2 Functional Relationships(s)
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1 The other two human CYP inhibitors were classified as strong inhibitors of CYP2A: 8-methoxypsoralen (CYP2A6) and alpha-naphthoflavone (CYP1A1/2). Methoxsalen cytochrome P450 family 2 subfamily A member 19 Sus scrofa
2 These results of this study suggest that 8-MOP is a potent, mechanism-based inhibitor of pig CYP2A activity in pig liver microsomes. Methoxsalen cytochrome P450 family 2 subfamily A member 19 Sus scrofa