Title : Repeated phencyclidine administration alters glutamate release and decreases GABA markers in the prefrontal cortex of rats.

Pub. Date : 2012 Mar

PMID : 21238466






1 Functional Relationships(s)
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1 These findings suggest that abnormal cortical glutamate transmission, possibly driven by pathological changes in GABA function in parvalbumin-positive fast-spiking interneurons, may underlie some of the cognitive deficits in schizophrenia. gamma-Aminobutyric Acid parvalbumin Rattus norvegicus