Pub. Date : 2010 Nov-Dec
PMID : 21229878
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of the study was to evaluate the expression profile of MMP-2, MMP-9 and their tissue inhibitors TIMP-1 and TIMP-2 at the mRNA level in human colorectal cancer cell line Caco-2 treated with IP6. | Phytic Acid | TIMP metallopeptidase inhibitor 2 | Homo sapiens |
| 2 | Treatment of cells with 2.5 mM IP6 at 12 h resulted in a strong increase in both TIMP-1 and TIMP-2 expression. | Phytic Acid | TIMP metallopeptidase inhibitor 2 | Homo sapiens |
| 3 | The results of this study show that IP6 modulates MMP-2, TIMP-1 and TIMP-2 genes expression in colon cancer cells at the transcriptional level in a way dependent on its concentration and time of interaction. | Phytic Acid | TIMP metallopeptidase inhibitor 2 | Homo sapiens |