Pub. Date : 2011 Jan 25
PMID : 21220345
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The second messenger phosphatidylinositol (3,4,5)-trisphosphate (PIP(3)), formed by the p110 family of PI3-kinases, promotes cellular growth, proliferation, and survival, in large part by activating the protein kinase Akt/PKB. | pip(3) | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Thus, growth factor stimulation of Akt signaling involves PIP(3) generation through the sequential activations of the p110 PI3-kinases and IPMK. | pip(3) | AKT serine/threonine kinase 1 | Homo sapiens |