Title : Silencing microRNA by interfering nanoparticles in mice.

Pub. Date : 2011 Mar

PMID : 21212128






2 Functional Relationships(s)
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1 Intravenous administration of 2 mg kg(-1) chemically modified anti-miR-122 complexed with iNOP-7 resulted in 83.2 +- 3.2% specific silencing of miR-122, which was accompanied by regulating gene expression in liver and lowering of plasma cholesterol. Cholesterol microRNA 122 Mus musculus
2 Intravenous administration of 2 mg kg(-1) chemically modified anti-miR-122 complexed with iNOP-7 resulted in 83.2 +- 3.2% specific silencing of miR-122, which was accompanied by regulating gene expression in liver and lowering of plasma cholesterol. Cholesterol microRNA 122 Mus musculus