Title : Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.

Pub. Date : 2011 Jan 15

PMID : 21211982






1 Functional Relationships(s)
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1 A Lineweaver-Burk plot and molecular modeling study showed that these hybrids targeted both the catalytic active site (CAS) and the peripheral anionic site (PAS) of AChE. Aminosalicylic Acid acetylcholinesterase (Cartwright blood group) Homo sapiens