Title : The calcium-sensing receptor-dependent regulation of cell-cell adhesion and keratinocyte differentiation requires Rho and filamin A.

Pub. Date : 2011 May

PMID : 21209619






1 Functional Relationships(s)
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1 Suppressing endogenous Rho A expression by small interfering RNA (siRNA)-mediated gene silencing blocked the Ca(2+)(o)-induced association of Fyn with E-cadherin and suppressed the Ca(2+)(o)-induced tyrosine phosphorylation of beta-, gamma-, and p120-catenin and formation of intercellular adherens junctions. Tyrosine FYN proto-oncogene, Src family tyrosine kinase Homo sapiens