Title : Nitric oxide-mediated vasodilation becomes independent of beta-adrenergic receptor activation with increased intensity of hypoxic exercise.

Pub. Date : 2011 Mar

PMID : 21193565






3 Functional Relationships(s)
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1 During propranolol alone, the rise in FVC (Delta from normoxic baseline) due to hypoxic exercise was 217 +- 29 and 415 +- 41 ml min(-1) 100 mmHg(-1) (10% and 20% of maximum, respectively). Propranolol CD59 molecule (CD59 blood group) Homo sapiens
2 Combined propranolol-l-NMMA infusion during hypoxic exercise attenuated DeltaFVC at 20% (352 +- 44 ml min(-1) 100 mmHg(-1); P < 0.001) but not at 10% (202 +- 28 ml min(-1) 100 mmHg(-1); P = 0.08) of maximum compared with propranolol alone. Propranolol CD59 molecule (CD59 blood group) Homo sapiens
3 Combined propranolol-l-NMMA infusion during hypoxic exercise attenuated DeltaFVC at 20% (352 +- 44 ml min(-1) 100 mmHg(-1); P < 0.001) but not at 10% (202 +- 28 ml min(-1) 100 mmHg(-1); P = 0.08) of maximum compared with propranolol alone. Propranolol CD59 molecule (CD59 blood group) Homo sapiens