Title : DNA repair defects sensitize cells to anticodon nuclease yeast killer toxins.

Pub. Date : 2011 Mar

PMID : 21188417






1 Functional Relationships(s)
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1 Because PaT and zymocin require the presence of the ELP3/TRM9-dependent wobble uridine modification 5-methoxy-carbonyl-methyl (mcm(5)) for tRNA cleavage, we analyzed toxin response in DNA repair mutants additionally lacking such tRNA modifications. Uridine tRNA (carboxymethyluridine(34)-5-O)-methyltransferase Saccharomyces cerevisiae S288C