Pub. Date : 2011 Mar
PMID : 21183731
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia. | Glucose | apolipoprotein C3 | Homo sapiens |
| 2 | ApoCIII induction by glucose is blunted by treatment with agonists of farnesoid X receptor and peroxisome proliferator-activated receptor-alpha but not liver X receptor, ie, nuclear receptors controlling triglyceride metabolism. | Glucose | apolipoprotein C3 | Homo sapiens |
| 3 | Moreover, in obese humans, plasma apoCIII protein correlates more closely with plasma fasting glucose and glucose excursion after oral glucose load than with insulin. | Glucose | apolipoprotein C3 | Homo sapiens |
| 4 | Moreover, in obese humans, plasma apoCIII protein correlates more closely with plasma fasting glucose and glucose excursion after oral glucose load than with insulin. | Glucose | apolipoprotein C3 | Homo sapiens |
| 5 | Moreover, in obese humans, plasma apoCIII protein correlates more closely with plasma fasting glucose and glucose excursion after oral glucose load than with insulin. | Glucose | apolipoprotein C3 | Homo sapiens |
| 6 | CONCLUSIONS: Glucose induces apoCIII transcription, which may represent a mechanism linking hyperglycemia, hypertriglyceridemia, and cardiovascular disease in type 2 diabetes. | Glucose | apolipoprotein C3 | Homo sapiens |