Title : The ACF1 complex is required for DNA double-strand break repair in human cells.

Pub. Date : 2010 Dec 22

PMID : 21172662






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 If the expression of ACF1 or SNF2H is suppressed, cells become extremely sensitive to X-rays and chemical treatments producing DSBs, and DSBs remain unrepaired. dsbs SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 Homo sapiens
2 If the expression of ACF1 or SNF2H is suppressed, cells become extremely sensitive to X-rays and chemical treatments producing DSBs, and DSBs remain unrepaired. dsbs SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 Homo sapiens
3 The KU70/80 complex becomes physically more associated with the chromatin-remodeling factors of the CHRAC complex, which includes ACF1, SNF2H, CHRAC15, and CHRAC17, after treatments producing DSBs. dsbs SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 Homo sapiens