Pub. Date : 2011 Feb 11
PMID : 21167176
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The function of the human voltage-gated sodium channel Na(V)1.5 is regulated in part by intracellular calcium signals. | Calcium | immunoglobulin lambda variable 2-18 | Homo sapiens |
| 2 | The ubiquitous calcium sensor protein calmodulin (CaM) is an important part of the complex calcium-sensing apparatus in Na(V)1.5. | Calcium | immunoglobulin lambda variable 2-18 | Homo sapiens |
| 3 | Sequence similarities between voltage-gated sodium channels and voltage-gated calcium channels suggest that the structure of the CaM-Na(V)1.5 IQ motif complex can serve as a general model for the interaction between CaM and ion channel IQ motifs under low-calcium conditions. | Calcium | immunoglobulin lambda variable 2-18 | Homo sapiens |