Pub. Date : 2011 Apr 15
PMID : 21167122
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of 8B20 cells with the UPP inhibitors, MG132 and clasto-lactacystin-beta-lactone, led to an increase in levels of p53 while treatment with non-proteasomal inhibitors did not alter p53 levels. | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | tumor protein p53 | Homo sapiens |
| 2 | Treatment of 8B20 cells with MG132 led to an increase in the half-life of p53. | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | tumor protein p53 | Homo sapiens |
| 3 | In vivo studies showed that MG132 induced p53 overexpression and reduced tumor growth, suggesting an important role of p53 stabilization in controlling melanoma. | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | tumor protein p53 | Homo sapiens |
| 4 | In vivo studies showed that MG132 induced p53 overexpression and reduced tumor growth, suggesting an important role of p53 stabilization in controlling melanoma. | benzyloxycarbonylleucyl-leucyl-leucine aldehyde | tumor protein p53 | Homo sapiens |