Title : Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability.

Pub. Date : 2011 Jul

PMID : 21163582






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Progesterone receptor antagonist CDB-4124 increases depression-like behavior in mice without affecting locomotor ability. telapristone acetate progesterone receptor Mus musculus
2 We administered the classic progesterone receptor antagonist mifepristone (RU-38486) and the specific progesterone receptor antagonist CDB-4124 to mice that had been primed with progesterone for five days, and found that both compounds induced FST immobility reliably, robustly, and in a dose-dependent fashion. telapristone acetate progesterone receptor Mus musculus