Title : All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein.

Pub. Date : 2010 Dec 16

PMID : 21159206






2 Functional Relationships(s)
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1 All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein. Tretinoin BCL2 associated X, apoptosis regulator Homo sapiens
2 In further examination, we found that the ATRA-induced apoptosis in GIST-T1 cells was accompanied by the down-regulated expression of survivin and up-regulated expression of Bax protein. Tretinoin BCL2 associated X, apoptosis regulator Homo sapiens