Title : Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.

Pub. Date : 2011 Feb 18

PMID : 21156789






2 Functional Relationships(s)
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1 Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK. ursolic acid tumor protein p53 Homo sapiens
2 Induction of DRs was independent of p53 because UA induced DR4 and DR5 in HCT116 p53(-/-) cells. ursolic acid tumor protein p53 Homo sapiens