Title : Differential involvement of α4β2, α7 and α9α10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro.

Pub. Date : 2011 Apr

PMID : 21146628






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Inhibition of alpha7 and alpha9(alpha10) nAChRs with methyllicaconitine resulted in considerable augmentation of CD40-mediated B lymphocyte proliferation in cells of all genotypes; stimulation of alpha4beta2 nAChRs with epibatidine increased the IgM-mediated proliferation of the wild-type and alpha7(-/-), but not beta2(-/-) cells. nachrs hemoglobin, beta adult minor chain Mus musculus