Title : [Effect of dexamethasone on expression of hypoxia inducible factor-1α and vascular endothelial growth factor in hypoxic mice].

Pub. Date : 2006 Apr 20

PMID : 21144299






6 Functional Relationships(s)
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1 [Effect of dexamethasone on expression of hypoxia inducible factor-1alpha and vascular endothelial growth factor in hypoxic mice]. Dexamethasone vascular endothelial growth factor A Mus musculus
2 The aim of this study is to observe the effect of dexamethasone on expression of hypoxia inducible factor 1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in lung tissues of hypoxic mice, and to investigate the relationship between hypoxia and angiogenesis and mechanism of dexamethasone. Dexamethasone vascular endothelial growth factor A Mus musculus
3 The aim of this study is to observe the effect of dexamethasone on expression of hypoxia inducible factor 1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in lung tissues of hypoxic mice, and to investigate the relationship between hypoxia and angiogenesis and mechanism of dexamethasone. Dexamethasone vascular endothelial growth factor A Mus musculus
4 The aim of this study is to observe the effect of dexamethasone on expression of hypoxia inducible factor 1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in lung tissues of hypoxic mice, and to investigate the relationship between hypoxia and angiogenesis and mechanism of dexamethasone. Dexamethasone vascular endothelial growth factor A Mus musculus
5 Compared with hypoxia group, expression of HIF-1alpha and VEGF decreased dramatically in hypoxia+dexamethasone group (P < 0.05). Dexamethasone vascular endothelial growth factor A Mus musculus
6 Dexamethasone can inhibit the expression of VEGF and HIF-1alpha of hypoxic mice and it may have anti-angiogenetic effect. Dexamethasone vascular endothelial growth factor A Mus musculus