Title : Increasing the antitumor efficacy of doxorubicin-loaded liposomes with peptides anchored via a chelator lipid.

Pub. Date : 2011 Sep

PMID : 21142652






2 Functional Relationships(s)
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1 Our results show that when engrafted with p15-RGR, a His-tagged peptide containing a sequence purported to bind platelet-derived growth factor receptor beta (PDGFRbeta), NTA(3)-DTDA-containing Caelyx (3NTA-Caelyx) can be targeted to NIH-3T3 cells in vitro, leading to increased cytotoxicity compared with non-targeted 3NTA-Caelyx. liposomal doxorubicin cyclin dependent kinase inhibitor 2B Mus musculus
2 Our results show that when engrafted with p15-RGR, a His-tagged peptide containing a sequence purported to bind platelet-derived growth factor receptor beta (PDGFRbeta), NTA(3)-DTDA-containing Caelyx (3NTA-Caelyx) can be targeted to NIH-3T3 cells in vitro, leading to increased cytotoxicity compared with non-targeted 3NTA-Caelyx. liposomal doxorubicin cyclin dependent kinase inhibitor 2B Mus musculus