Title : Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt.

Pub. Date : 2011 Feb

PMID : 21136025






3 Functional Relationships(s)
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1 Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt. tert-Butylhydroperoxide AKT serine/threonine kinase 1 Homo sapiens
2 The pre-treatment with Cur3 decreased t-BHP-induced ERK1/2 phosphorylation and increased t-BHP-induced Akt phosporylation but did not affect the phosphorylation of p38 or JNK. tert-Butylhydroperoxide AKT serine/threonine kinase 1 Homo sapiens
3 These results suggest that the ERK1/2 and PI3K/Akt signaling pathways could be involved in the protective effects of Cur3 against t-BHP-induced damage in HUVECs. tert-Butylhydroperoxide AKT serine/threonine kinase 1 Homo sapiens