Pub. Date : 2011 Feb
PMID : 21136025
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt. | tert-Butylhydroperoxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | The pre-treatment with Cur3 decreased t-BHP-induced ERK1/2 phosphorylation and increased t-BHP-induced Akt phosporylation but did not affect the phosphorylation of p38 or JNK. | tert-Butylhydroperoxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | These results suggest that the ERK1/2 and PI3K/Akt signaling pathways could be involved in the protective effects of Cur3 against t-BHP-induced damage in HUVECs. | tert-Butylhydroperoxide | AKT serine/threonine kinase 1 | Homo sapiens |