Title : [The relationship of expression of GLUT1,HIF-1α and the uptake of FDG in non-small cell lung cancer].

Pub. Date : 2007 Dec 20

PMID : 21129310






2 Functional Relationships(s)
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1 BACKGROUND: It has been known that facilitative glucose transporter(GLUT) is the main carrier which intervenes the glucose uptake of cell,and there is a significant correlation between GLUT1 and cancer.The expression of GLUT1 in lung cancer has close relationship with the uptake of 18fluoro-2-deoxyglucose(FDG) of lung cancer,and the expression of GLUT1 is regulated by hypoxia inducible factor-1(HIF-1).The aim of this study is to investigate the relationship among expression of GLUT1,HIF-1alpha and the uptake of FDG in non-small cell lung cancer(NSCLC). 18fluoro-2-deoxyglucose single-strand-selective monofunctional uracil-DNA glycosylase 1 Homo sapiens
2 BACKGROUND: It has been known that facilitative glucose transporter(GLUT) is the main carrier which intervenes the glucose uptake of cell,and there is a significant correlation between GLUT1 and cancer.The expression of GLUT1 in lung cancer has close relationship with the uptake of 18fluoro-2-deoxyglucose(FDG) of lung cancer,and the expression of GLUT1 is regulated by hypoxia inducible factor-1(HIF-1).The aim of this study is to investigate the relationship among expression of GLUT1,HIF-1alpha and the uptake of FDG in non-small cell lung cancer(NSCLC). 18fluoro-2-deoxyglucose single-strand-selective monofunctional uracil-DNA glycosylase 1 Homo sapiens